Research highlights

This section showcases recent research findings enabled by FinnGen data and the Finnish biobank participants. Below you can find several examples of how FinnGen is helping to increase our understanding of the genetic drivers of human diseases, pinpointing possible therapeutic targets.
The power of a genetic isolate: Hundreds of novel genetic discoveries from the FinnGen study
A map of Finland with chromosomes surrounding it, and human figures representing all stages of human lifespan.
New results from the FinnGen research consortium demonstrate the undeniable benefits of Finnish health research environment for genomic research. Among the wealth of novel genetic discoveries are…
Beyond Mendel: FinnGen study sheds new light on well-established theories of genetic inheritance
A drawing of a family with two children, showing the classical inheritance model, with question marks on top.
A large-scale biobank-based study performed in Finland has discovered several new disease genes as well as new insights on how known genetic factors affect disease. The study highlights an…
Genetic predisposition to sedentary behaviour increases the risk of cardiovascular diseases
Legs of a woman jogging.
Researchers have shown for the first time that genetic predisposition to sedentary behaviour is associated with a higher risk of developing the most common cardiovascular diseases. A high genetic…
Researchers identify new genes predisposing to inflammation of the iris
Closeup of a human eye.
An international study led by the University of Oulu and Oulu University Hospital has identified six genetic regions associated with the inflammation of the eye's iris, also known as anterior…
The genetic findings reveal the reason for the exceptionally high prevalence of cleft palate in Finland
a row of wooden blocks engraved with DNA double helix patterns. One block in the middle is red and stands out from the others.
The prevalence of cleft palate in Finland is more than twice the European average. A research team identified genetic variants that explain this phenomenon, as well as a regional distribution where…
A significant genetic defect linked to female infertility identified in Finland
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A study has discovered a genetic defect that affects the maturation of oocytes, leading to infertility in women. This discovery provides new insights into the genetic causes of infertility and may…
Researchers discover dozens of new genes associated with disc herniations
An abstract human figure with a red glowing sphere at the lower back.
Lumbar disc herniation is one of the most common structural changes in the lower back and the most common cause of radiating pain, or sciatica, in the leg.
Study Identifies Severe Side Effects of the Most Effective Schizophrenia Medication
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A recent Finnish study found that pneumonia and severe gastrointestinal complications are more common with the most effective schizophrenia medication than previously thought. These side effects…
Six genetic regions associated with normal pressure hydrocephalus identified
Abstract illustration of human brain in different shades of blue.
A new study by the University of Eastern Finland and partners identified new genetic variants associated with normal pressure hydrocephalus (NPH). Published in Neurology, the study is the first large…
New insights into genetic triggers of X chromosome loss illuminate links to autoimmunity and cancer
A profile of a woman made out of colorful mosaic pieces.
An international team of researchers has uncovered genetic factors that predispose women to a genetic phenomenon where some cells lose one of their two X chromosomes.